
The reporter learned from the Institute of Zoology, Chinese Academy of Sciences that the Institute, Researcher Liu Guanghaui, Researcher Qu Jing, Researcher Zhang Weiqi, Researcher Zhang Weiqi of the National Bioinformatics Center, Researcher Song Moshi of the Institute of Zoology, Chinese Academy of the Sciences, and researcher Wang of the Capital Medical University, took six years to systematically analyzed the molecular-cell dynamic response of the human body to chronic single movement and long-term regular movements for the first time, announced that the kidney was the main transponder for the impact of the motor-the endogenous metabolite Betabine Betabine, Messenger for aging delays, targets the suppression of natural immune hub kinase TBK1, and coordinates the suppression of inflammation and dedication to the aging process.该结果于6月25日在北京奥尔拉斯(Orras of Beijing)发表在国际学术期刊“牢房”中。 △情绪健康益处和分子机制在这项研究中,研究人员否认了第一次将反应与可量化的多态动态网络拟合反应的复杂系统生物学问题。在一次慢性运动和长期定期运动后显示出生理适应和机制。 The study analyzes the molecular dividing between acute and long-term exercise for the first time: acute exercise stimulates "survival stress-type" metabolic storms and oxidative damage, while long-term exercise drives health-oriented metabolism-immune homeostasis remodeling, and established Adaptation system with metabolic reprogramming, immune rejuvenation, epigenetic stability maintenance and improving antioxidant capacity as列。同时,长期训练会重新介绍肠道微生物结构,防止病原体共生细菌的丰度,并协调人体的能量代谢。 △口头甜菜碱有效降低了肝脏DEC在老老鼠中。对照组(左);干预组(右)基于小鼠运动模型,研究发现长期运动可以显着提高肾甜菜蛋白的水平。老年大鼠的口服干预实验表明,贝特因延长了健康的寿命,并显着改善了五个绩效指标:改善了代谢能力,提高肾脏功能,改善运动协调,行为减少,例如行为和增强的发展功能性。病理组织学和单细胞转录组的综合分析进一步证实,贝丁因对多器官衰老的延迟,尤其是肾脏和骨骼肌的延迟有影响。通常,该研究系统地分析了主要分子枢纽以重塑人类生理和延迟衰老,为科学反染色开辟了新的途径,并为促进健康衰老研究提供了重要的科学基础。 。